2-(o-Tolylazo)-p-cresol

Base Information

• Chemical Name: 2-(o-Tolylazo)-p-cresol
• CAS No.: 6370-43-0
• Molecular Formula: C14H14 N2 O
• Molecular Weight: 226.278
• European Community (EC) Number: 228-881-9
• UNII: 3GB6UR3XRC
• DSSTox Substance ID: DTXSID001023510
• Nikkaji Number: J33.576B
• Mol file: 6370-43-0.mol

Synonyms:Oleal Yellow RE;SOLVENT YELLOW 12;2-(o-Tolylazo)-p-cresol;C.I. Solvent Yellow 12;6370-43-0;Zlut rozpoustedlova 12 [Czech];Zlut rozpoustedlova 12;C.I. 11860;EINECS 228-881-9;3GB6UR3XRC;BRN 0958875;4-methyl-2-[(2-methylphenyl)diazenyl]phenol;Phenol, 4-methyl-2-((2-methylphenyl)azo)-;4-16-00-00200 (Beilstein Handbook Reference);Phenol, 4-methyl-2-[(2-methylphenyl)azo]-;YELLOW HA;UNII-3GB6UR3XRC;CI SOLVENT YELLOW 12;SCHEMBL1615338;SCHEMBL11955367;DTXSID001023510;P-CRESOL, 2-(O-TOLYLAZO)-;2-(2'-methylphenylazo)-4-methylphenol;CI 11860;LS-98267;C.I.11860;PHENOL, 4-METHYL-2-(2-(2-METHYLPHENYL)DIAZENYL)-

Chemical Property of 2-(o-Tolylazo)-p-cresol

Chemical Property:

• Vapor Pressure: 2.18E-05mmHg at 25°C
• Melting Point: 98°C
• Refractive Index: 1.58
• Boiling Point: 397 °C at 760 mmHg
• PKA: 8.87±0.43(Predicted)
• Flash Point: 254.5 °C
• PSA: 44.95000
• Density: 1.09 g/cm³
• LogP: 4.42440
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 226.110613074
• Heavy Atom Count: 17
• Complexity: 267

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)O)N=NC2=CC=CC=C2C

Technology Process of 2-(o-Tolylazo)-p-cresol

There total 2 articles about 2-(o-Tolylazo)-p-cresol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-cresol (106-44-5) + 2-methylbenzene diazonium (17333-74-3) → 2-(2'-methylphenylazo)-4-methylphenol (6370-43-0)

Guidance literature:

With alkali;

Reference yield:

→ 2-(2'-methylphenylazo)-4-methylphenol (6370-43-0)

Guidance literature:

o-Toluidin, 1. Diazotieren 2. Kuppeln mit p-Kresol/alkohol. Na2CO3-Lsg.;

Reference yield: 70.0%

tris(triphenylphosphine)chloroiridium (16070-58-9) + 2-(2'-methylphenylazo)-4-methylphenol (6370-43-0) → [Ir(H)(PPh3)2(2-(2'-methylphenylazo)-4-methylphenol(-2H))] (866599-71-5)

Guidance literature:

With triethylamine; In ethanol; 2-(2'-methylphenylazo)-4-methylphenol dissolved in EtOH; soln. was purged with a stream of N2 for 5 min; Et3N and Ir(PPh3)3Cl added; mixt. refluxed under N2 atm. for 12 h; solvent evapd.; residue purified by thin layer chromy. on silica gel plate (benzene as eluent); blue band sepd.; extd. (MeCN); solvent slowly evapd.; elem. anal.;

DOI:10.1016/j.jorganchem.2005.05.025

upstream raw materials:

p-cresol

2-methylbenzene diazonium

Downstream raw materials:

[RuCl(P(C₆H₅)3)2(OC₆H₃(CH₃)NNC₆H₃(CH₃))]

{Cu(C₆H₄(CH₃)NNC₆H₃(CH₃)(O))2}

[Ir(H)(PPh₃)2(2-(2'-methylphenylazo)-4-methylphenol(-2H))]

[Ir(Cl)(PPh₃)2(2-(2'-methylphenylazo)-4-methylphenol(-2H))]