2-bromo-1,3-diisopropoxybenzene

Base Information

• Chemical Name: 2-bromo-1,3-diisopropoxybenzene
• CAS No.: 1369880-56-7
• Molecular Formula: C₁₂H₁₇BrO₂
• Molecular Weight: 273.17
• Mol file: 1369880-56-7.mol

Synonyms:2-bromo-1,3-diisopropoxybenzene

Chemical Property of 2-bromo-1,3-diisopropoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-1,3-diisopropoxybenzene

There total 2 articles about 2-bromo-1,3-diisopropoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.2%

2-bromoresorcinol (6751-75-3) + isopropyl alcohol (67-63-0,8013-70-5) → 2-bromo-1,3-diisopropoxybenzene (1369880-56-7)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; at 0 - 20 ℃; for 15.0167h; Inert atmosphere;

DOI:10.1021/ol502492b

Reference yield: 77.0%

2,6-di(isopropoxy)benzoic acid (79128-15-7) → 2-bromo-1,3-diisopropoxybenzene (1369880-56-7)

Guidance literature:

With silver carbonate; copper(ll) bromide; palladium dichloride; In tetrahydrofuran; at 110 ℃; for 24h;

DOI:10.1016/j.tetlet.2013.03.135

Reference yield: 87.9%

2-bromo-1,3-diisopropoxybenzene (1369880-56-7) → 2,6-bis(isopropoxy)phenylboronic acid

Guidance literature:

2-bromo-1,3-diisopropoxybenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol502492b

upstream raw materials:

2,6-di(isopropoxy)benzoic acid

2-bromoresorcinol

isopropyl alcohol