Mepindolol

Base Information

• Chemical Name: Mepindolol
• CAS No.: 23694-81-7
• Molecular Formula: C15H22 N2 O2
• Molecular Weight: 262.352
• Hs Code.: 2933990090
• European Community (EC) Number: 245-831-1
• UNII: 00Q31ER368
• DSSTox Substance ID: DTXSID40865110
• Nikkaji Number: J20.368H
• Wikipedia: Mepindolol
• Wikidata: Q2760233
• NCI Thesaurus Code: C84659
• Metabolomics Workbench ID: 154328
• ChEMBL ID: CHEMBL65717
• Mol file: 23694-81-7.mol

Synonyms:1-(isopropylamino)-3-(2-methylindol-4-yloxy)-2-propanol sulfate;bis(4-(2-hydroxy-3-isopropylaminopropoxy)-2-methylindol) sulfate;Corindolan;LF 17-895;mepindolol;mepindolol sulfate (2:1);SH E 222

Chemical Property of Mepindolol

Chemical Property:

• Vapor Pressure: 1.24E-09mmHg at 25°C
• Melting Point: 100-102° (Seeman). Also reported as 95-97° (Troxler)
• Boiling Point: 469.9°Cat760mmHg
• PKA: pKa 8.90 (Uncertain)
• Flash Point: 238°C
• PSA: 57.28000
• Density: 1.131g/cm³
• LogP: 2.60490
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly)
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 262.168127949
• Heavy Atom Count: 19
• Complexity: 273

Purity/Quality:

99% ^*data from raw suppliers

rac Mepindolol-d7 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)C)O
• Uses: Mepindolol is a non-selective β-adrenoceptor blocking agent. Mepindolol is used in the treatment of glaucoma. (rac Mepindolol-d7) Mepindolol is a non-selective β-adrenoceptor blocking agent. Mepindolol is used in the treatment of glaucoma.

Technology Process of Mepindolol

There total 1 articles about Mepindolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ mepindolol (23694-81-7)

Guidance literature:

4-Hydroxy-2-methyl-indol (2b) 1. (18) 2. H2, Pd;

DOI:10.1002/hlca.19710540805

Refernces

• 1、 -. "ANTIHYPERTENSIVE THERAPY". . . Retrieved 2009/09/08.