Technology Process of 23-O-benzoyl-23-O-demycinosyltylosin
There total 9 articles about 23-O-benzoyl-23-O-demycinosyltylosin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 63 percent / triethylamine / CH2Cl2 / 44 h / 25 °C
2: 86 percent / methanol / 90 h / 25 °C
With
methanol; triethylamine;
In
dichloromethane;
DOI:10.1039/P19890000775
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 37 percent / anhydrous potassium carbonate / 5 h / 60 - 65 °C
2: 76 percent / anhydrous tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 25 °C
3: 86 percent / N-(3-dimethylaminopropyl)-N'-ethylcarbodi-imide hydrochloride, pyridine, trifluoroacetic acid / dimethylsulfoxide / 19 h / 25 °C / other reagent: diethylcarbodi-imide
4: 1.) sodium methoxide, 2.) triethylamine / 1.) methanol, 25 deg C, 1 h, 2.) 40 deg C, 67 h
5: 82 percent / acetone / 18 h / 25 °C
6: 63 percent / triethylamine / CH2Cl2 / 44 h / 25 °C
7: 86 percent / methanol / 90 h / 25 °C
With
pyridine; methanol; tetrabutyl ammonium fluoride; sodium methylate; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide; acetone;
DOI:10.1039/P19890000775
