benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

Base Information

Chemical Name:benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate
CAS No.:1357928-24-5
Molecular Formula:C₃₄H₃₇N₇O₁₁
Molecular Weight:719.708
Hs Code.:

benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

Synonyms:benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

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Chemical Property of benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

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Technology Process of benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

There total 8 articles about benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1738-68-7
Gly-OBz

: 1357928-25-6
C₂₂H₂₃N₉O₇

: 1357928-24-5
benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 20h;

Reference yield:

: 1738-68-7
Gly-OBz

: 1357928-23-4
C₂₈H₃₀N₈O₉

: 1357928-24-5
benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 20h;

Reference yield:

: 68892-42-2
N-isobutyryl-2'-deoxyguanosine

: 1357928-24-5
benzyl ((((2R,5R)-3-(((2-(benzyloxy)-2-oxoethyl)carbamoyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methoxy)carbonyl)glycinate

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h

With N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile;