3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

Base Information

Chemical Name:3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester
CAS No.:1140039-89-9
Molecular Formula:C₂₅H₂₆N₂O₃
Molecular Weight:402.493
Hs Code.:

Synonyms:3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

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Chemical Property of 3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

Chemical Property:

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Technology Process of 3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

There total 6 articles about 3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1140039-74-2
3-(2-tert-Butoxycarbonylamino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

: 1140039-89-9
3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

Guidance literature:: With sodium carbonate; aniline; In 1,4-dioxane; 4HCl;

Reference yield:

: 457098-91-8
[5-Methyl-2-(1,2,3,4-tetrahydro-quinolin-3-ylmethoxy)-phenyl]-carbamic acid tert-butyl ester

: 1140039-89-9
3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane

2: sodium carbonate; aniline / 1,4-dioxane; 4HCl

With dmap; sodium carbonate; N-ethyl-N,N-diisopropylamine; aniline; In 1,4-dioxane; 4HCl; dichloromethane;

Reference yield:

: 177198-62-8,177198-64-0,177202-62-9
1,2,3,4-Tetrahydro-quinoline-3-carboxylic acid methyl ester

: 1140039-89-9
3-(2-Amino-4-methyl-phenoxymethyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / diethyl ether

2: diisopropyl (E)-azodicarboxylate; triphenylphosphine / tetrahydrofuran

3: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane

4: sodium carbonate; aniline / 1,4-dioxane; 4HCl

With dmap; sodium hydroxide; sodium carbonate; diisopropyl (E)-azodicarboxylate; N-ethyl-N,N-diisopropylamine; aniline; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; 4HCl; diethyl ether; dichloromethane;