6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

Base Information

Chemical Name:6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester
CAS No.:1035798-53-8
Molecular Formula:C₂₅H₃₄O₄S
Molecular Weight:430.609
Hs Code.:

Synonyms:6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

Suppliers and Price of 6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

There total 4 articles about 6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 109719-47-3
1-tert-Butoxycarbonylmethyl-3,3-dimethyl-5-trimethylsilanyloxy-bicyclo[3.1.0]hexane-6-carboxylic acid ethyl ester

: 69442-54-2
<α-(phenylthio)vinyl>-triphenylphosphonium tetrafluoroborate

: 1035798-53-8
6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

Guidance literature:: With potassium fluoride; 18-crown-6 ether; In acetonitrile; at 82 ℃; Title compound not separated from byproducts;
DOI:10.1021/jo00227a042

Reference yield:

: 22748-16-9
4,4-dimethylcyclopent-2-ene-1-one

: 1035798-53-8
6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: 1.) Et₃N, 2.) CuSO₄ / 1.) DMF, 135 deg C, 2.) benzene

3: 95 percent / KF, 18-crown-6 / acetonitrile / 82 °C

With potassium fluoride; 18-crown-6 ether; copper(II) sulfate; triethylamine; In acetonitrile;
DOI:10.1021/jo00227a042

Reference yield:

: 109719-46-2
(4,4-Dimethyl-2-oxo-cyclopentyl)-acetic acid tert-butyl ester

: 1035798-53-8
6a-tert-Butoxycarbonylmethyl-5,5-dimethyl-3-phenylsulfanyl-1,2,4,5,6,6a-hexahydro-pentalene-1-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Et₃N, 2.) CuSO₄ / 1.) DMF, 135 deg C, 2.) benzene

2: 95 percent / KF, 18-crown-6 / acetonitrile / 82 °C

With potassium fluoride; 18-crown-6 ether; copper(II) sulfate; triethylamine; In acetonitrile;
DOI:10.1021/jo00227a042