2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile

Base Information

Chemical Name:2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile
CAS No.:1158804-43-3
Molecular Formula:C₁₉H₂₅N₅
Molecular Weight:323.441
Hs Code.:

Synonyms:2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile

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Chemical Property of 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile

Chemical Property:

Boiling Point:574.5±60.0 °C(Predicted)
Density:1.132±0.06 g/cm3(Predicted)

Purity/Quality:

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Technology Process of 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile

There total 2 articles about 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1158804-56-8
2-(4-((2-amino-4-((2,4,6-trimethylbenzenesulfonyl)oxy)-6-methylpyrimidin-5-yl)methyl)phenyl)acetonitrile

: 110-58-7
n-Pentylamine

: 1158804-43-3
2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile

Guidance literature:: 2-(4-((2-amino-4-((2,4,6-trimethylbenzenesulfonyl)oxy)-6-methylpyrimidin-5-yl)methyl)phenyl)acetonitrile; n-Pentylamine; With trifluoroacetic acid; In acetic acid butyl ester; at 120 ℃; for 2h;

With sodium hydroxide; In acetic acid butyl ester; water; at 20 ℃;

Reference yield:

: 1256595-68-2
2-(4-((2-amino-4-((2,4,6-triisopropylbenzenesulfonyl)oxy)-6-methylpyrimidin-5-yl)methyl)phenyl)acetonitrile

: 110-58-7
n-Pentylamine

: 1158804-43-3
2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)-acetonitrile

Guidance literature:: 2-(4-((2-amino-4-((2,4,6-triisopropylbenzenesulfonyl)oxy)-6-methylpyrimidin-5-yl)methyl)phenyl)acetonitrile; n-Pentylamine; With trifluoroacetic acid; In acetic acid butyl ester; at 120 ℃; for 6h;

With lithium hydroxide; In tetrahydrofuran; water; toluene; at 40 ℃;