2-methylidene-3-oxocyclopentanecarbonitrile

Base Information

• Chemical Name: 2-methylidene-3-oxocyclopentanecarbonitrile
• CAS No.: 82093-32-1
• Molecular Formula: C₇H₇NO
• Molecular Weight: 121.139
• Mol file: 82093-32-1.mol

Synonyms:Cyclopentanecarbonitrile,2-methylene-3-oxo-, (?à)-; NSC 318815

Chemical Property of 2-methylidene-3-oxocyclopentanecarbonitrile

Chemical Property:

• Vapor Pressure: 0.00334mmHg at 25°C
• Boiling Point: 282.5°Cat760mmHg
• Flash Point: 124.7°C
• Density: 1.07g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methylidene-3-oxocyclopentanecarbonitrile

There total 9 articles about 2-methylidene-3-oxocyclopentanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl 3-oxo 1-cyclopentanecarbonitrile (112496-86-3) → 2-methylene 3-oxo cyclopentane carbonitrile (90380-02-2,82093-32-1)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/S0040-4020(01)89959-2

Reference yield:

3-oxo 2-phenylsulfonylmethyl cyclopentane carbonitrile (110946-11-7) → 2-methylene 3-oxo cyclopentane carbonitrile (90380-02-2,82093-32-1)

Guidance literature:

With aluminum oxide;

DOI:10.1016/S0040-4039(00)83866-6

Reference yield:

2-(hydroxymethylene)-3-cyanocyclopentanone ethylene ketal (82093-31-0) → 2-methylene 3-oxo cyclopentane carbonitrile (90380-02-2,82093-32-1)

Guidance literature:

With hydrogenchloride; In acetone; for 12h; Ambient temperature;

DOI:10.1021/jo00138a020

upstream raw materials:

2-methyl 3-oxo 1-cyclopentanecarbonitrile

2-(hydroxymethylene)-3-cyanocyclopentanone ethylene ketal

3-oxo 2-phenylsulfinylmethyl cyclopentane

3-oxo 2-phenylsulfonylmethyl cyclopentane carbonitrile