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alpha-Glycyrrhizin

Base Information Edit
  • Chemical Name:alpha-Glycyrrhizin
  • CAS No.:83896-44-0
  • Molecular Formula:C42H62O16
  • Molecular Weight:822.945
  • Hs Code.:
  • UNII:80ARS2076G
  • DSSTox Substance ID:DTXSID401314947
  • Nikkaji Number:J129.908E
  • ChEMBL ID:CHEMBL4280362
  • Mol file:83896-44-0.mol
alpha-Glycyrrhizin

Synonyms:alpha-Glycyrrhizin;83896-44-0;18-alpha-Glycyrrhizin;18-alpha-Glycyrrhizic acid;18-alpha-Glycyrrhizinic acid;Isoglycyrrhizinic acid;18alpha-Glycylrrhizin;80ARS2076G;(2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aS,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid;alpha-D-Glucopyranosiduronic acid, (3-beta,18-alpha,20-beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-;alpha-D-Glucopyranosiduronic acid, (3beta,18alpha,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-;C42-H62-O16;.ALPHA.-GLYCYRRHIZIN;UNII-80ARS2076G;18.ALPHA.-GLYCYRRHIZIN;CHEMBL4280362;DTXSID401314947;18.ALPHA.-GLYCYRRHIZINIC ACID;LS-71617;(3.BETA.,18.ALPHA.,20.BETA.)-20-CARBOXY-11-OXO-30-NOROLEAN-12-EN-3-YL 2-O-.BETA.-D-GLUCOPYRANURONOSYL-.ALPHA.-D-GLUCOPYRANOSIDURONIC ACID;.ALPHA.-D-GLUCOPYRANOSIDURONIC ACID, (3.BETA.,18.ALPHA.,20.BETA.)-20-CARBOXY-11-OXO-30-NOROLEAN-12-EN-3-YL 2-O-.BETA.-D-GLUCOPYRANURONOSYL-

Suppliers and Price of alpha-Glycyrrhizin
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 2 raw suppliers
Chemical Property of alpha-Glycyrrhizin Edit
Chemical Property:
  • Vapor Pressure:0mmHg at 25°C 
  • Boiling Point:971.4°C at 760 mmHg 
  • Flash Point:288.1°C 
  • PSA:267.04000 
  • Density:1.43g/cm3 
  • LogP:2.24560 
  • XLogP3:3.7
  • Hydrogen Bond Donor Count:8
  • Hydrogen Bond Acceptor Count:16
  • Rotatable Bond Count:7
  • Exact Mass:822.40378589
  • Heavy Atom Count:58
  • Complexity:1730
Purity/Quality:

99% *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C
  • Isomeric SMILES:C[C@]12CC[C@](C[C@@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O
  • Uses 18α-Glycyrrhizic Acid is a derivative of Glycyrrhizic Acid (G735150), a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects.
Technology Process of alpha-Glycyrrhizin

There total 7 articles about alpha-Glycyrrhizin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide; In water; at 20 ℃; for 0.25h;
Guidance literature:
Multi-step reaction with 2 steps
1: 10 wt% Pd(OH)2 on carbon; hydrogen / ethyl acetate; ethanol / 16 h / 20 °C
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hypochlorite; sodium hydrogencarbonate / water / 0.25 h / 20 °C
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 10 wt% Pd(OH)2 on carbon; hydrogen; sodium hydrogencarbonate; potassium bromide; In ethanol; water; ethyl acetate;
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