Technology Process of C38H54N4O2
There total 9 articles about C38H54N4O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3,5-di-tert-butyl-2-hydroxybenzaldehyde; 1,2-diaminocyclohexane monohydrochloride;
In
methanol;
at 20 ℃;
for 2h;
Molecular sieve;
Inert atmosphere;
3-[3-(1H-imidazol-1-yl)propyl]-5-tert-butyl-2-hydroxybenzaldehyde;
With
triethylamine;
In
methanol; ethanol;
at 20 ℃;
Inert atmosphere;
Molecular sieve;
DOI:10.1021/ja9033999
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: phosphorus tribromide / toluene / 2 h / Reflux; Inert atmosphere
2.1: potassium carbonate / acetonitrile / 24 h / 80 °C / Inert atmosphere
3.1: boron tribromide / dichloromethane / 12.5 h / -78 - 20 °C / Inert atmosphere
3.2: 0 °C
4.1: triethylamine; magnesium chloride / tetrahydrofuran / 3 h / Inert atmosphere; Reflux
5.1: methanol / 2 h / 20 °C / Molecular sieve; Inert atmosphere
5.2: 20 °C / Inert atmosphere; Molecular sieve
With
boron tribromide; phosphorus tribromide; potassium carbonate; triethylamine; magnesium chloride;
In
tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;
DOI:10.1021/ja9033999
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetonitrile / 24 h / 80 °C / Inert atmosphere
2.1: boron tribromide / dichloromethane / 12.5 h / -78 - 20 °C / Inert atmosphere
2.2: 0 °C
3.1: triethylamine; magnesium chloride / tetrahydrofuran / 3 h / Inert atmosphere; Reflux
4.1: methanol / 2 h / 20 °C / Molecular sieve; Inert atmosphere
4.2: 20 °C / Inert atmosphere; Molecular sieve
With
boron tribromide; potassium carbonate; triethylamine; magnesium chloride;
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1021/ja9033999
