Floctafenic acid

Base Information

Chemical Name:Floctafenic acid
CAS No.:36783-34-3
Molecular Formula:C₁₇H₁₁F₃N₂O₂
Molecular Weight:332.282
Hs Code.:2933499090
European Community (EC) Number:807-265-9
UNII:K9D19L5WTV
DSSTox Substance ID:DTXSID60190254
Nikkaji Number:J900.918C
Wikidata:Q27282128
Mol file:36783-34-3.mol

Synonyms:floctafenic acid

Suppliers and Price of Floctafenic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
FloctafenicAcid
10mg
$ 150.00

Medical Isotopes, Inc.
FloctafenicAcid
100 mg
$ 2200.00

AK Scientific
Floctafenicacid
500mg
$ 2242.00

Total 4 raw suppliers

Chemical Property of Floctafenic acid

Chemical Property:

Vapor Pressure:2.67E-09mmHg at 25°C
Boiling Point:461.1°Cat760mmHg
Flash Point:232.7°C
PSA：62.22000
Density:1.451g/cm³
LogP:4.76840
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:4.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:332.07726208
Heavy Atom Count:24
Complexity:458

Purity/Quality:

99% ^*data from raw suppliers

FloctafenicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)O)NC2=C3C=CC=C(C3=NC=C2)C(F)(F)F
Uses Floctafenic Acid is an impurity of Floctafenine (F401700).

Technology Process of Floctafenic acid

There total 1 articles about Floctafenic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36783-34-3
2-((8-(trifluoromethyl)quinolin-4-yl)amino)benzoic acid

Guidance literature:: Entspr. Me-Ester, Na2CO3;

Reference yield:

: 36783-34-3
2-((8-(trifluoromethyl)quinolin-4-yl)amino)benzoic acid

: 49712-37-0
2-(8-trifluoromethyl-quinolin-4-ylamino)-benzoic acid butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂; DMF / 2 h / Heating

2: Et₃N / CH₂Cl₂ / 2 h / Heating

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1002/ardp.200400959

Reference yield:

: 36783-34-3
2-((8-(trifluoromethyl)quinolin-4-yl)amino)benzoic acid

: 2-(8-trifluoromethyl-quinolin-4-ylamino)-benzoic acid isopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂; DMF / 2 h / Heating

2: Et₃N / CH₂Cl₂ / 2 h / Heating

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1002/ardp.200400959