3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

Base Information

Chemical Name:3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester
CAS No.:887326-69-4
Molecular Formula:C₄₇H₇₁NO₁₂Si₂
Molecular Weight:898.251
Hs Code.:

3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(<i>tert</i>-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2<i>H</i>-pyran-3-yloxy]-2-(<i>tert</i>-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2<i>H</i>-pyran-3-yl ester

Synonyms:3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

Suppliers and Price of 3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

There total 6 articles about 3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 887326-76-3
(R)-2-Benzyloxycarbonylamino-3-{4-[(2S,5R,6S)-6-(tert-butyl-dimethyl-silanyloxymethyl)-5-hydroxy-5,6-dihydro-2H-pyran-2-yloxy]-phenyl}-propionic acid methyl ester

: 887326-69-4
3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Pd₂(dba)3*CHCl₃; PPh₃ / CH₂Cl₂

2: NaBH₄ / -24 °C

3: DCC

With sodium tetrahydroborate; dicyclohexyl-carbodiimide; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; triphenylphosphine; In dichloromethane;
DOI:10.1021/ol060254a

Reference yield:

: (D)-N-(carboxybenzyloxy)tyrosine methyl ester

: 887326-69-4
3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1: Pd₂(dba)3*CHCl₃; PPh₃ / CH₂Cl₂

2: NaBH₄ / methanol; CH₂Cl₂ / -24 °C

3: Pd₂(dba)3*CHCl₃; PPh₃ / CH₂Cl₂

4: NaBH₄ / -24 °C

5: DCC

With sodium tetrahydroborate; dicyclohexyl-carbodiimide; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; triphenylphosphine; In methanol; dichloromethane;
DOI:10.1021/ol060254a

Reference yield:

: 623157-43-7
(2S,6S)-carbonic acid tert-butyl ester 6-(tert-butyl-dimethyl-silanyloxymethyl)-4-oxo-2,3-dihydro-6H-pyran-2-yl ester

: 887326-69-4
3-methyl-butyric acid 6-[6-[4-(2-benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-phenoxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1: Pd₂(dba)3*CHCl₃; PPh₃ / CH₂Cl₂

2: NaBH₄ / methanol; CH₂Cl₂ / -24 °C

3: Pd₂(dba)3*CHCl₃; PPh₃ / CH₂Cl₂

4: NaBH₄ / -24 °C

5: DCC

With sodium tetrahydroborate; dicyclohexyl-carbodiimide; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; triphenylphosphine; In methanol; dichloromethane;
DOI:10.1021/ol060254a