N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester

Base Information

• Chemical Name: N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester
• CAS No.: 162894-84-0
• Molecular Formula: C₃₈H₃₁F₅N₂O₁₄S₂
• Molecular Weight: 898.793

Synonyms:N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester

Chemical Property of N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester

There total 5 articles about N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Nα-(fluoren-9-ylmethoxycarbonyl)-L-serine pentafluorophenyl ester (86061-05-4) + Acetic acid (2R,3S,4R,5R)-3-acetoxy-2-acetoxymethyl-6-bromo-5-(3,5-dioxo-[1,2,4]dithiazolidin-4-yl)-tetrahydro-pyran-4-yl ester → Nα-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester (162894-84-0)

Guidance literature:

With 3 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; at 25 ℃; for 3h;

DOI:10.1021/ja953529i

Reference yield: 63.8%

Nα-(fluoren-9-ylmethoxycarbonyl)-L-serine pentafluorophenyl ester (86061-05-4) + O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl) trichloroacetimidate (162894-83-9) → Nα-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester (162894-84-0)

Guidance literature:

With AgOTfl; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1039/P19950000405

Reference yield:

3,4,6-tri-O-acetyl-2-deoxy-2-(dithiasuccinoylamino)-D-β-glucopyranosyl bromide (162894-81-7) → Nα-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester (162894-84-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 88.5 percent / acetone; H₂O / 3 h

2: 67 percent / K₂CO₃, molecular sieves 3A / CH₂Cl₂ / Ambient temperature

3: 63.8 percent / AgOTfl / CH₂Cl₂ / 12 h / Ambient temperature

With 3 A molecular sieve; potassium carbonate; In dichloromethane; water; acetone;

DOI:10.1039/P19950000405

upstream raw materials:

N^α-(fluoren-9-ylmethoxycarbonyl)-L-serine pentafluorophenyl ester

O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl) trichloroacetimidate

3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranose

3,4,6-tri-O-acetyl-2-deoxy-2-(dithiasuccinoylamino)-D-β-glucopyranosyl bromide

Downstream raw materials:

O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-N^α-(fluoren-9-ylmethoxycarbonyl)-L-serine pentafluorophenyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 162894-84-0 N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send