2-AMINO-N-PHENYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE

Base Information

• Chemical Name: 2-AMINO-N-PHENYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
• CAS No.: 60598-68-7
• Molecular Formula: C₁₅H₁₆N₂OS
• Molecular Weight: 272.371
• Mol file: 60598-68-7.mol

Synonyms:2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid phenyl-amide

Chemical Property of 2-AMINO-N-PHENYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-N-phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-AMINO-N-PHENYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE

There total 5 articles about 2-AMINO-N-PHENYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

cyanoacetanilide (621-03-4) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid phenyl-amide (60598-68-7)

Guidance literature:

With morpholine; aluminum oxide; sulfur; for 0.166667h; microwave irradiation;

DOI:10.1081/SCC-200057268

Reference yield: 62.0%

α-cyclohexylidenecyanoacetanilide (89733-13-1) → 2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid phenyl-amide (60598-68-7)

Guidance literature:

With morpholine; sulfur; In ethanol; at 90 ℃; for 5h;

DOI:10.1021/acs.jmedchem.7b00020

Reference yield:

cyanoacetanilide (621-03-4) → 2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid phenyl-amide (60598-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium acetate, glacial AcOH / benzene / Heating

2: sulphur, diethylamine / ethanol / 50 °C

With ammonium acetate; sulfur; acetic acid; diethylamine; In ethanol; benzene;

upstream raw materials:

α-cyclohexylidenecyanoacetanilide

cyanoacetanilide

cyclohexanone

aniline

Downstream raw materials:

2-methyl-5,6,7,8-tetrahydrobenzo<4,5>thieno<2,3-d>pyrimidin-4(3H)-one

N-(3-Phenylcarbamoyl-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl)-malonamic acid ethyl ester

2-chloroacetylamino-3-anilido-4,5,6,7-tetrahydrobenzothiophene

2-Acetimidoylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid phenylamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 60598-68-7 2-AMINO-N-PHENYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send