N-(3-Nitrobenzylidene)-P-toluidine

Base Information

• Chemical Name: N-(3-Nitrobenzylidene)-P-toluidine
• CAS No.: 17064-95-8
• Molecular Formula: C14H12N2O2
• Molecular Weight: 240.261
• European Community (EC) Number: 653-042-2
• NSC Number: 157691
• DSSTox Substance ID: DTXSID30303278
• Nikkaji Number: J824.086H
• Mol file: 17064-95-8.mol

Synonyms:17064-95-8;NSC157691;SCHEMBL2136470;DTXSID30303278;XTPAJQOAWUWVLP-XNTDXEJSSA-N;N-(4-tolyl)-3-nitrobenzylideneamine;AKOS024333401;NSC-157691;N-(3-NITROBENZYLIDENE)-P-TOLUIDINE;[1-(3-nitro-phenyl)-meth-(E)-ylidene]-p-tolyl-amine;N-3-nitrobenzylidene-p-toluidine N-p-toluidene-3-nitrobenzeneamine;N-[(3-nitrophenyl)methylene]-4-methylbenzenamine N-(4-methylphenyl)-3-nitrobenzylideneamine

Chemical Property of N-(3-Nitrobenzylidene)-P-toluidine

Chemical Property:

• Vapor Pressure: 2.78E-06mmHg at 25°C
• Boiling Point: 401.2°C at 760 mmHg
• Flash Point: 196.5°C
• Density: 1.14g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 240.089877630
• Heavy Atom Count: 18
• Complexity: 303

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)N=CC2=CC(=CC=C2)[N+](=O)[O-]

Technology Process of N-(3-Nitrobenzylidene)-P-toluidine

There total 4 articles about N-(3-Nitrobenzylidene)-P-toluidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-nitro-benzaldehyde (99-61-6) + p-toluidine (106-49-0,12221-03-3) → N-(3-nitrobenzylidene)-4-methylbenzenamine (17064-95-8)

Guidance literature:

DOI:10.1021/ja0034388

Reference yield: 99.0%

3-nitro-benzaldehyde (99-61-6) + p-toluidine (106-49-0,12221-03-3) → (E)-4-methyl-N-(3-nitrobenzylidene)aniline (17064-95-8)

Guidance literature:

In neat (no solvent); at 20 ℃; Green chemistry;

DOI:10.1002/jccs.201800486

Reference yield:

3-Nitrobenzyl alcohol (619-25-0) + p-toluidine (106-49-0,12221-03-3) → N-(3-nitrobenzylidene)-4-methylbenzenamine (17064-95-8)

Guidance literature:

With Ru nanoparticles loaded benzene-1,3,5-tricarbohydrazide with benzene-1,4-dicarboxaldehyde generated covalent organic framework; air; In neat (no solvent); at 80 ℃; for 22h;

DOI:10.1021/acs.inorgchem.7b03077

upstream raw materials:

3-nitro-benzaldehyde

p-toluidine

3-Nitrobenzyl alcohol

Downstream raw materials:

N-(3-nitro-benzyl)-p-toluidine

4,4,6-trimethyl-2-(3-nitro-phenyl)-1,2,3,4-tetrahydro-quinoline

Refernces

• 1、 Tigineh, Getinet Tamiru,Liu, Ling-Kang. "Systematic studies on mechanochemical synthesis: Schiff bases from solid aromatic primary amines and aldehydes". . p. 1729 - 1737. Retrieved 2019/06/21.
• 2、 Chen, Gong-Jun,Li, Xiao-Bo,Zhao, Chen-Chen,Ma, Hui-Chao,Kan, Jing-Lan,Xin, Yu-Bin,Chen, Cheng-Xia,Dong, Yu-Bin. "Ru Nanoparticles-Loaded Covalent Organic Framework for Solvent-Free One-Pot Tandem Reactions in Air". supporting information. p. 2678 - 2685. Retrieved 2018/03/13.