N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Base Information

Chemical Name:N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid
CAS No.:100020-41-5
Molecular Formula:C₂₄H₂₁Cl₂N₅O₆
Molecular Weight:546.367
Hs Code.:

N-<3,5-dichloro-4-<N-<(2-amino-4-hydroxy-6-quinazolinyl)methyl>prop-2-ynylamino>benzoyl>-L-glutamic acid

Synonyms:N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Suppliers and Price of N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

There total 4 articles about N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 100020-45-9
diethyl N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamate

: 100020-41-5
N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 18h; Ambient temperature;
DOI:10.1021/jm00154a007

Reference yield:

: 77766-62-2
2-amino-6-(bromomethyl)-4-hydroxyquinazoline hydrobromide

: 100020-41-5
N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 12 percent / CaCO₃ / N,N-dimethyl-acetamide / 144 h / Ambient temperature

2: 91 percent / aq. NaOH / ethanol / 18 h / Ambient temperature

With sodium hydroxide; calcium carbonate; In ethanol; N,N-dimethyl acetamide;
DOI:10.1021/jm00154a007

Reference yield:

: 76858-72-5
diethyl N-(4-(prop-2-ynylamino)benzoyl)-L-glutamate

: 100020-41-5
N-<3,5-dichloro-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / SO₂Cl₂ / CHCl₃ / Ambient temperature

2: 12 percent / CaCO₃ / N,N-dimethyl-acetamide / 144 h / Ambient temperature

3: 91 percent / aq. NaOH / ethanol / 18 h / Ambient temperature

With sodium hydroxide; sulfuryl dichloride; calcium carbonate; In ethanol; chloroform; N,N-dimethyl acetamide;
DOI:10.1021/jm00154a007