N⁶-(5-(2,5-dimethoxyphenyl)pentyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

Base Information

• Chemical Name: N⁶-(5-(2,5-dimethoxyphenyl)pentyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
• CAS No.: 1612146-41-4
• Molecular Formula: C₂₃H₃₅N₃O₂S
• Molecular Weight: 417.616

Synonyms:N⁶-(5-(2,5-dimethoxyphenyl)pentyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

Chemical Property of N⁶-(5-(2,5-dimethoxyphenyl)pentyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁶-(5-(2,5-dimethoxyphenyl)pentyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

There total 4 articles about N⁶-(5-(2,5-dimethoxyphenyl)pentyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

5-(2,5-dimethoxyphenyl)pentanal (1310092-12-6) + 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole (104617-86-9) → N6-(5-(2,5-dimethoxyphenyl)pentyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (1612146-41-4)

Guidance literature:

5-(2,5-dimethoxyphenyl)pentanal; 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole; In dichloromethane; for 1h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In methanol; dichloromethane; at 20 ℃; for 36h; Inert atmosphere;

DOI:10.1016/j.bmc.2016.08.021

Reference yield:

ethyl 5-(2,5-dimethoxyphenyl)pentanoate (1612146-40-3) → N6-(5-(2,5-dimethoxyphenyl)pentyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (1612146-41-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diisobutylaluminium hydride / toluene; hexane / 2 h / -78 °C / Inert atmosphere

2.1: dichloromethane / 1 h / Inert atmosphere

2.2: 36 h / 20 °C / Inert atmosphere

With diisobutylaluminium hydride; In hexane; dichloromethane; toluene;

DOI:10.1016/j.bmc.2016.08.021

Reference yield:

ethyl 5-(2,5-dimethoxyphenyl)pent-4-enoate → N6-(5-(2,5-dimethoxyphenyl)pentyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (1612146-41-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogen; palladium 10% on activated carbon / ethanol / 2 h / 20 °C

2.1: diisobutylaluminium hydride / toluene; hexane / 2 h / -78 °C / Inert atmosphere

3.1: dichloromethane / 1 h / Inert atmosphere

3.2: 36 h / 20 °C / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; diisobutylaluminium hydride; In ethanol; hexane; dichloromethane; toluene;

DOI:10.1016/j.bmc.2016.08.021

upstream raw materials:

ethyl 5-(2,5-dimethoxyphenyl)pentanoate

5-(2,5-dimethoxyphenyl)pentanal

2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole

Downstream raw materials:

2-(5-((2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)(propyl)amino)pentyl)benzene-1,4-diol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1612146-41-4 N⁶-(5-(2,5-dimethoxyphenyl)pentyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send