(R)-1--4-methylpiperazine

Base Information

Chemical Name:(R)-1--4-methylpiperazine
CAS No.:157303-84-9
Molecular Formula:C₂₁H₂₅N₃O₃
Molecular Weight:367.448
Hs Code.:

(R)-1-<N-(benzyloxycarbonyl)-2-phenylglycyl>-4-methylpiperazine

Synonyms:(R)-1--4-methylpiperazine

Suppliers and Price of (R)-1--4-methylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-1--4-methylpiperazine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-1--4-methylpiperazine

There total 1 articles about (R)-1--4-methylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 109-01-3
1-methyl-piperazine

: 17609-52-8
Z-D-phenylglycine

: 157303-84-9
(R)-1--4-methylpiperazine

Guidance literature:: With diethyl cyanophosphonate; triethylamine; In N,N-dimethyl-formamide; for 4h; Ambient temperature;
DOI:10.1248/cpb.42.690

Reference yield:

: 157303-84-9
(R)-1--4-methylpiperazine

: [2,2-Dimethyl-prop-(E)-ylidene]-[(R)-2-(4-methyl-piperazin-1-yl)-1-phenyl-ethyl]-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 33percent HBr/AcOH / Ambient temperature

2: LiAlH₄ / tetrahydrofuran / 2 h / Heating

3: Na₂SO₄ / benzene / 3 h / Ambient temperature

With lithium aluminium tetrahydride; hydrogen bromide; acetic acid; sodium sulfate; In tetrahydrofuran; benzene;
DOI:10.1248/cpb.42.690

Reference yield:

: 157303-84-9
(R)-1--4-methylpiperazine

: 128350-76-5
(R)-N-(2,2-dimethylpropyl)-1-phenyl-2-(4-methylpiperazinyl)ethylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 33percent HBr/AcOH / Ambient temperature

2: LiAlH₄ / tetrahydrofuran / 2 h / Heating

3: Na₂SO₄ / benzene / 3 h / Ambient temperature

4: NaBH₄ / ethanol / 0.5 h

With sodium tetrahydroborate; lithium aluminium tetrahydride; hydrogen bromide; acetic acid; sodium sulfate; In tetrahydrofuran; ethanol; benzene;
DOI:10.1248/cpb.42.690