N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide

Base Information

• Chemical Name: N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide
• CAS No.: 1262669-82-8
• Molecular Formula: C₁₉H₂₀ClNO₂S
• Molecular Weight: 361.892
• Mol file: 1262669-82-8.mol

Synonyms:N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide

Chemical Property of N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide

There total 1 articles about N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-chloro-5-hexyne (10297-06-0) + phenyl toluenesulfonamide (68-34-8) → N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide (1262669-82-8)

Guidance literature:

phenyl toluenesulfonamide; With pyridine; oxygen; sodium carbonate; copper dichloride; In toluene; at 70 ℃;

1-chloro-5-hexyne; In toluene; at 70 ℃; for 8h;

DOI:10.1039/c0cc02736g

Reference yield:

N-(6-chlorohex-1-yn-1yl)-4-methyl-N-phenylbenzenesulfonamide (1262669-82-8) → (Z)-6-chloro-N-phenyl-N-tosylhex-2-enamide (1262670-10-9) + (E)-6-chloro-N-phenyl-N-tosylhex-2-enamide (1262669-98-6)

Guidance literature:

With pyridine N-oxide; gold(III) tribromide; In tetrahydrofuran; at 20 ℃; for 18h; optical yield given as %de; regiospecific reaction; Inert atmosphere;

DOI:10.1039/c0cc02736g

upstream raw materials:

1-chloro-5-hexyne

phenyl toluenesulfonamide

Downstream raw materials:

(Z)-6-chloro-N-phenyl-N-tosylhex-2-enamide

(E)-6-chloro-N-phenyl-N-tosylhex-2-enamide