2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid

Base Information

Chemical Name:2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid
CAS No.:1240040-80-5
Molecular Formula:C₂₄H₂₈ClNO₅
Molecular Weight:445.943
Hs Code.:

Synonyms:2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid

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Chemical Property of 2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid

Chemical Property:

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Technology Process of 2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid

There total 1 articles about 2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1240040-79-2
tert-butyl 2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoate

: 1240040-80-5
2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃;

Reference yield:

: 1240040-80-5
2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid

: 127168-84-7
5-bromoisoindoline

: 1240040-82-7
ethyl N-[4-(1-{1-(4-chlorophenyl)-2-oxo-2-[5-bromo-1,3-dihydro-2H-isoindol-2-yl]ethyl}butyl)benzoyl]-β-alaninate

Guidance literature:: 2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid; With N-ethyl-N,N-diisopropylamine; HATU; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 1h;

5-bromoisoindoline; In 1-methyl-pyrrolidin-2-one; at 20 ℃;

Reference yield:

: 1203686-59-2
4-(trifluoromethyl)isoindoline hydrochloride

: 1240040-80-5
2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid

: C₃₃H₃₄ClF₃N₂O₄

Guidance literature:: 2-(4-chlorophenyl)-3-(4-{[(3-ethoxy-3-oxopropyl)amino]carbonyl}phenyl)hexanoic acid; With HATU; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 1h;

4-(trifluoromethyl)isoindoline hydrochloride; With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃;