5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene

Base Information

• Chemical Name: 5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene
• CAS No.: 943231-28-5
• Molecular Formula: C₆₂H₆₂F₆O₂
• Molecular Weight: 953.163
• Mol file: 943231-28-5.mol

Synonyms:5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene

Chemical Property of 5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene

There total 1 articles about 5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

4-trifluoromethylphenylacetylene (705-31-7) + p-tert-Butylcalix<4>arene 1,3-bistriflate (172878-84-1) → 5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene (943231-28-5)

Guidance literature:

With copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; bis-triphenylphosphine-palladium(II) chloride; In toluene; for 24h; Heating;

DOI:10.1002/chem.200700615

Reference yield: 100.0%

5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene (943231-28-5) + bis(pentafluorophenyl)zinc (1799-90-2) → (C6F5)2Zn2((OC6H2(C(CH3)3)CH2)2(C6H2(C(CH3)3)(CCC6H4CF3)CH2)2) (947622-78-8)

Guidance literature:

In hexane; toluene; under N2; soln. of Zn(C6F5)2 in hexane added to soln. of ligand in toluene; stirred at room temp. for 8 h; volatiles evapd.;

DOI:10.1021/om070213y

Reference yield: 100.0%

5,11,17,23-tetra(tert-butyl)-25,27-dihydroxy-26,28-bis[p-(trifluoromethyl)phenylethynyl]calix[4]arene (943231-28-5) + diethylzinc (557-20-0) → (C2H5)2Zn2((OC6H2(C(CH3)3)CH2)2(C6H2(C(CH3)3)(CCC6H4CF3)CH2)2) (947622-73-3)

Guidance literature:

In hexane; toluene; under N2; soln. of ZnEt2 in hexane added to soln. of ligand in toluene; stirred at room temp. for 8 h; volatiles evapd.;

DOI:10.1021/om070213y

upstream raw materials:

4-trifluoromethylphenylacetylene

p-tert-Butylcalix<4>arene 1,3-bistriflate

Downstream raw materials:

(C₆F₅)2Zn₂((OC₆H₂(C(CH₃)3)CH₂)2(C₆H₂(C(CH₃)3)(CCC₆H₄CF₃)CH₂)2)

(C₂H₅)2Zn₂((OC₆H₂(C(CH₃)3)CH₂)2(C₆H₂(C(CH₃)3)(CCC₆H₄CF₃)CH₂)2)

(CH₃)2Zn₂((OC₆H₂(C(CH₃)3)CH₂)2(C₆H₂(C(CH₃)3)(CCC₆H₄CF₃)CH₂)2)