Gentamicin sulphate

Base Information

• Chemical Name: Gentamicin sulphate
• CAS No.: 1405-41-0
• Molecular Formula: C21H43N5O7^.H2SO4
• Molecular Weight: 575.67
• Hs Code.: 29419010
• European Community (EC) Number: 215-778-9
• ChEMBL ID: CHEMBL1200643
• Mol file: 1405-41-0.mol

Synonyms:Gentamicine sulfate;Gentamicin, sulfate (salt);gentamicin sulfate (water content 10%);GENTAMICIN SULPHATE;Gentamicin (sulfate);Prestwick_240;MFCD00270181;D09PEQ;CHEMBL1200643;RDEIXVOBVLKYNT-HDZPSJEVSA-N;HMS1568O22;HMS2095O22;HMS3712O22;AKOS026750085;CCG-220160;AS-35221;SR-01000872641;SR-01000872641-1;Gentamicin sulfate, meets EP, USP testing specifications;Gentamicin sulfate, meets USP testing specifications, powder;Gentamicin sulfate salt, potency: >=590 mug Gentamicin base per mg;Gentamicin sulfate, European Pharmacopoeia (EP) Reference Standard;Gentamicin sulfate from Micromonospora purpurea, ~700 U/mg dried material;Gentamicin sulfate salt, powder, BioReagent, suitable for cell culture;Gentamicin sulfate, United States Pharmacopeia (USP) Reference Standard;Gentamicin for peak identification, European Pharmacopoeia (EP) Reference Standard;Gentamicin Sulfate, Pharmaceutical Secondary Standard;Certified Reference Material;(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol

Chemical Property of Gentamicin sulphate

Chemical Property:

• Appearance/Colour: White crystalline powder
• Melting Point: 218-237 °C
• Boiling Point: 797.6 °C at 760 mmHg
• Flash Point: 436.2 °C
• PSA: 719.38000
• Density: ==
• LogP: -1.26180
• Storage Temp.: 2-8°C
• Solubility.: H2O: 50 mg/mL As stock solution, store at −20°
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 26
• Hydrogen Bond Acceptor Count: 40
• Rotatable Bond Count: 19
• Exact Mass: 1487.86917571
• Heavy Atom Count: 101
• Complexity: 1930

Purity/Quality:

99% HPLC ^*data from raw suppliers

Gentamicin Sulfate Salt, C Complex ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 42/43
• Safety Statements: 23-36/37-45-22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)N.CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CCC(O3)CN)N)N)N)O.OS(=O)(=O)O
• Isomeric SMILES: C[C@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)N.C[C@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)NC.C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC[C@H](O3)CN)N)N)N)O.OS(=O)(=O)O
• Recent EU Clinical Trials: A randomised controlled trial to compare the clinical effectiveness and safety of gentamicin and ceftriaxone in the treatment of gonorrhoea.
• Uses: This compound is a complex mixture of the sulfates of gentamycin Cl, gentamycin CIA and gentamycin C2. Pharmaceutical incompatibilites include amphotericin, cephalosporins, erythromycin, heparin, penicillins, sodium bicarbonate, and sulfadiazine sodium. It is used as topical and systemic broad-spectrum antibiotic with bactericidal action; also used in ophthalmic drugs. Inhibits protein synthesis by binding to L6 protein of 50S ribosomal subunit. Antibacterial. Antibiotic complex consists of three closely related components, gentamicins C1, C2, C1a, and also gentamicin A which differs from the other members of the complex but is similar to Kanamycin C. Gentamicin C1: R1=R2=CH3 Gentamicin C2: R1=CH3; R2=H Gentamicin C1A: R1=R2=H Different viscosity grades available. Please inquire
• Therapeutic Function: Antibacterial