5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid

Base Information

Chemical Name:5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid
CAS No.:439578-86-6
Molecular Formula:C₁₆H₁₂BrN₃O₂S₂
Molecular Weight:422.326
Hs Code.:

Synonyms:5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid

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Technology Process of 5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid

There total 1 articles about 5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 439578-85-5
6-Bromo-N-(5-bromo-2-thiazolyl)pyridin-2-amine

: 84889-58-7
5-mercapto-2-methyl-benzoic acid

: 439578-86-6
5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid

Guidance literature:: With sodium methylate; In tetrahydrofuran; methanol; P₂O₅;

Reference yield: 76.0%

: 439578-86-6
5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid

: C₁₆H₁₅N₃OS₂

Guidance literature:: 5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 19h;

With sodium tetrahydroborate; In water; Further stages.;
DOI:10.1016/j.bmcl.2007.11.076

Reference yield:

: 439578-86-6
5-[[2-[N-(6-Bromopyridin-2-yl)amino]thiazol-5-yl]thio]-2-methylbenzoic Acid

: 151-18-8,60585-38-8
2-cyanoethylamine

: 1012060-84-2
C₁₉H₁₆BrN₅OS₂

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmcl.2007.11.076