Trimethaphan camsylate

Base Information

• Chemical Name: Trimethaphan camsylate
• CAS No.: 68-91-7
• Deprecated CAS: 20814-88-4,3482-31-3,54421-91-9,878787-83-8
• Molecular Formula: C₁₀H₁₅O₄S*C₂₂H₂₅N₂OS
• Molecular Weight: 596.812
• European Community (EC) Number: 200-696-8
• DSSTox Substance ID: DTXSID3023710
• Wikipedia: Trimetaphan_camsilate
• Wikidata: Q7842197
• NCI Thesaurus Code: C66639
• ChEMBL ID: CHEMBL1245
• Mol file: 68-91-7.mol

Synonyms:Arfonad;trimethaphan camphor sulfonate;trimethaphan camsylate

Chemical Property of Trimethaphan camsylate

Chemical Property:

• Melting Point: 245 °C (decomp)
• PSA: 131.50000
• LogP: 5.53950
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 596.23786473
• Heavy Atom Count: 41
• Complexity: 905

Purity/Quality:

98%min ^*data from raw suppliers

TRIMETAPHAN CAMSILATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(C2CCC1(C(=O)C2)CS(=O)(=O)[O-])C.C1CC2C3C(C[S+]2C1)N(C(=O)N3CC4=CC=CC=C4)CC5=CC=CC=C5
• Clinical Use: This ganglionic blocking agent is short acting and isused for certain neurosurgical procedures in which excessivebleeding obscures the operative field. Certain craniotomiesare included among these operations. The actionof the drug is direct vasodilation, and because of its transientaction, it is subject to minute-by-minute control.This fleeting action, however, makes it useless for hypertensivecontrol. The drug is ineffective when given orally.The usual route of administration is intravenous.Trimethaphan camsylate is indicated in the treatment ofhypertensive emergencies to reduce blood pressure rapidly.These emergencies may include pulmonary hypertensionassociated with systemic hypertension and acutedissecting aneurysm.