ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide

Base Information

• Chemical Name: ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide
• CAS No.: 1027519-90-9
• Molecular Formula: C₄₂H₈₁NO₆S₂Si₃
• Molecular Weight: 844.497
• Mol file: 1027519-90-9.mol

Synonyms:ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide

Chemical Property of ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide

There total 1 articles about ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoic acid methyl ester → ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide (1027519-90-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: aq. LiOH / tetrahydrofuran / 20 °C

2.1: CDI; DBU / tetrahydrofuran / 0.5 h / 20 °C

2.2: DBU / tetrahydrofuran

With lithium hydroxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,1'-carbonyldiimidazole; In tetrahydrofuran;

DOI:10.1248/cpb.48.1332

Reference yield: 82.0%

ethanesulfonic acid (7-{3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenylsulfanyl-butyl]-cyclopentyl}-heptanoyl)-amide (1027519-90-9) → ethanesulfonic acid{7-[3,5-dihydroxy-2-(3-hydroxy-4-phenylsulphanylbutyl)cyclopentyl]heptanoyl}amide

Guidance literature:

With pyridine; hydrogen fluoride; In acetonitrile; at 0 ℃; for 8h;

DOI:10.1248/cpb.48.1332