2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester

Base Information

• Chemical Name: 2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester
• CAS No.: 199007-53-9
• Molecular Formula: C₃₅H₃₄N₂O₂
• Molecular Weight: 514.667
• Mol file: 199007-53-9.mol

Synonyms:2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester

Chemical Property of 2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester

There total 1 articles about 2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(2Z,4E)-2-Benzyl-5-(1-trityl-1H-imidazol-4-yl)-penta-2,4-dienoic acid methyl ester → 2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester (199007-53-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; chloroform; for 2h; under 2844.3 Torr; Ambient temperature;

DOI:10.1016/S0968-0896(97)00134-X

Reference yield: 97.0%

2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester (199007-53-9) → 2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid

Guidance literature:

With sodium hydroxide; In methanol; at 50 ℃; for 3h;

DOI:10.1016/S0968-0896(97)00134-X

Reference yield:

2-benzyl-5-(N-triphenylmethylimidazol-4-yl)pentanoic acid methyl ester (199007-53-9) → 2-Benzyl-5-(1H-imidazol-4-yl)-pentanoic acid; hydrochloride

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / 10percent aq. NaOH / methanol / 3 h / 50 °C

2: 65 percent / conc. aq. HCl / dioxane / 2 h / Heating

With hydrogenchloride; sodium hydroxide; In 1,4-dioxane; methanol;

DOI:10.1016/S0968-0896(97)00134-X