3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester

Base Information

• Chemical Name: 3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester
• CAS No.: 74427-72-8
• Molecular Formula: C₄₆H₄₄N₆O₈
• Molecular Weight: 808.891
• Mol file: 74427-72-8.mol

Synonyms:3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester

Chemical Property of 3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester

There total 2 articles about 3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

mesoporphyrin-II-biscarboxylic acid (69423-12-7) + 1-nitro-4-trifluoroacetoxy-benzene (658-78-6) → 3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester (74427-72-8)

Guidance literature:

In pyridine; Ambient temperature;

DOI:10.1021/ja00539a009

Reference yield:

meso-porphyrin-II-dimethyl ester (62222-14-4) → 3-{(1Z,4Z,9Z,15Z)-7,17-Diethyl-3,8,13,18-tetramethyl-12-[2-(4-nitro-phenoxycarbonyl)-ethyl]-porphyrin-2-yl}-propionic acid 4-nitro-phenyl ester (74427-72-8)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl,CF₃COOH / 48 h

2: 88 percent / pyridine / Ambient temperature

With hydrogenchloride; trifluoroacetic acid; In pyridine;

DOI:10.1021/ja00539a009

upstream raw materials:

mesoporphyrin-II-biscarboxylic acid

1-nitro-4-trifluoroacetoxy-benzene

meso-porphyrin-II-dimethyl ester