1,6-Dideoxy-1,1-bis(ethylsulfonyl)-L-Mannitol

Base Information

• Chemical Name: 1,6-Dideoxy-1,1-bis(ethylsulfonyl)-L-Mannitol
• CAS No.: 54253-49-5
• Molecular Formula: C10H22 O8 S2
• Molecular Weight: 334.412
• Hs Code.: 2905590090
• Mol file: 54253-49-5.mol

Synonyms:NSC 263754

Chemical Property of 1,6-Dideoxy-1,1-bis(ethylsulfonyl)-L-Mannitol

Chemical Property:

• Vapor Pressure: 3.29E-24mmHg at 25°C
• Melting Point: 178-180 °C
• Boiling Point: 724.1°Cat760mmHg
• PKA: 11.84±0.20(Predicted)
• Flash Point: 391.7°C
• PSA: 165.96000
• Density: 1.469g/cm³
• LogP: -0.15050
• Storage Temp.: 2-8°C

Purity/Quality:

99.3% ^*data from raw suppliers

(2R,3R,4S,5S)-1,1-Bis(ethylsulfonyl)-hexane-2,3,4,5-tetraol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-Rhamnose Bis(ethylsulfone) is a useful chemical intermediate.

Technology Process of 1,6-Dideoxy-1,1-bis(ethylsulfonyl)-L-Mannitol

There total 7 articles about 1,6-Dideoxy-1,1-bis(ethylsulfonyl)-L-Mannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-rhamnose diethyl dithioacetal (6748-70-5) → 1,1-diethylsulfonyl-L-rhamnose (54253-49-5)

Guidance literature:

With 1,4-dioxane; perpropionic acid; water;

DOI:10.1039/jr9550003544

Reference yield:

L-Rhamnose (3615-41-6,478518-52-4) → 1,1-diethylsulfonyl-L-rhamnose (54253-49-5)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HCl

2: MCPBA / dioxane

With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In 1,4-dioxane;

DOI:10.1021/ja00424a051

Reference yield:

diethyl dithioacetal L-fucose (5328-49-4) → L-1,1-bis-ethanesulfonyl-1,6-dideoxy-galactitol (54253-49-5,115115-43-0)

Guidance literature:

With 1,4-dioxane; perpropionic acid; water;

upstream raw materials:

L-rhamnose diethyl dithioacetal

L-Rhamnose

diethyl dithioacetal L-fucose

1,4-dioxane

Downstream raw materials:

5-deoxy-L-arabinose

biopterin

5-deoxy-2,3,4-O-triacetyl-L-arabinose-phenylhydrazone

5-deoxy-L-arabinose phenylhydrazone