6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil

Base Information

• Chemical Name: 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil
• CAS No.: 165960-76-9
• Molecular Formula: C₂₆H₄₀N₂O₆Si
• Molecular Weight: 504.699

Synonyms:6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil

Chemical Property of 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil

There total 3 articles about 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethylbenzaldehyde (5779-95-3) → 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil (165960-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) LDA / 1.) THF, -70 deg C, 1 h, 2.) THF, -70 deg C, 1 h

2: pyridine / 12 h / Ambient temperature

With pyridine; lithium diisopropyl amide;

DOI:10.1021/jm00015a008

Reference yield:

1-<<2-(tert-butyldimethylsiloxy)ethoxy>methyl>-5-ethyluracil (138192-34-4) → 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil (165960-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) LDA / 1.) THF, -70 deg C, 1 h, 2.) THF, -70 deg C, 1 h

2: pyridine / 12 h / Ambient temperature

With pyridine; lithium diisopropyl amide;

DOI:10.1021/jm00015a008

Reference yield:

acetic anhydride (108-24-7) + 1-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxymethyl]-6-[(3,5-dimethyl-phenyl)-hydroxy-methyl]-5-ethyl-1H-pyrimidine-2,4-dione (1026967-73-6) → 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil (165960-76-9)

Guidance literature:

With pyridine; for 12h; Yield given; Ambient temperature;

DOI:10.1021/jm00015a008

upstream raw materials:

acetic anhydride

1-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxymethyl]-6-[(3,5-dimethyl-phenyl)-hydroxy-methyl]-5-ethyl-1H-pyrimidine-2,4-dione

3,5-dimethylbenzaldehyde

1-<<2-(tert-butyldimethylsiloxy)ethoxy>methyl>-5-ethyluracil

Downstream raw materials:

6-(3,5-dimethylbenzyl)-5-ethyl-1-[(2-hydroxyethoxy)methyl]pyrimidine-2,4(1H,3H)-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 165960-76-9 6--1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-ethyluracil

Send

Send

Metric Ton KG G Pound L ML

Send

Send