1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol

Base Information

• Chemical Name: 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol
• CAS No.: 145167-60-8
• Molecular Formula: C₄₁H₄₄O₁₁
• Molecular Weight: 712.794

Synonyms:1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol

Chemical Property of 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol

There total 4 articles about 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1L*-2-O-<(tert-butyl)dimethylsilyl>-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol (145124-79-4,145167-56-2,145167-58-4,145212-14-2) → 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol (145167-60-8)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 24 ℃;

DOI:10.1002/hlca.19920750623

Reference yield: 20.0%

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl trichloroacetimidate (74808-09-6) + myo-Inositol orthoformate (98510-20-4) → 1L-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-myo-inositol (145167-57-3) + 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol (145167-60-8) + 1D-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-myo-inositol (145124-80-7) + 1D*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol (145167-59-5)

Guidance literature:

With 4 A molecular sieve; boron trifluoride diethyl etherate; In 1,4-dioxane; for 0.5h; Further byproducts given; Ambient temperature;

DOI:10.1002/hlca.19920750623

Reference yield:

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl trichloroacetimidate (74808-09-6) → 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol (145167-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 11 percent / 4 Angstroem molecular sieves, BF₃ * Et₂O / CH₂Cl₂ / a) room temperature, 1 h, b) 0 deg C, 30 min.

2: 87 percent / Bu₄NF * 3 H₂O / tetrahydrofuran / 24 °C

With 4 A molecular sieve; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;

DOI:10.1002/hlca.19920750623

upstream raw materials:

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl trichloroacetimidate

myo-Inositol orthoformate

1L*-2-O-<(tert-butyl)dimethylsilyl>-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol

(1R,3S,5S,6R,7S,8S,9S)-9-<(tert-butyl)dimethylsilyloxy>-2,4,10-tri-oxatricyclo<3.3.1.1^3,7>decane-6,8-diol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 145167-60-8 1L*-1,3,5-O-methylidyne-4-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-myo-inositol

Send

Send

Metric Ton KG G Pound L ML

Send

Send