Chemical Property of Strophanthin K
Chemical Property:
- Melting Point:195°C
- Refractive Index:1.6130 (estimate)
- Boiling Point:628.39°C (rough estimate)
- PKA:12.89±0.70(Predicted)
- PSA：210.90000
- Density:1.1625 (rough estimate)
- LogP:0.25750
- XLogP3:-0.8
- Hydrogen Bond Donor Count:6
- Hydrogen Bond Acceptor Count:14
- Rotatable Bond Count:8
- Exact Mass:710.35135639
- Heavy Atom Count:50
- Complexity:1330
- Purity/Quality:
-
99% *data from raw suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1C(C(CC(O1)OC2CCC3(C4CCC5(C(CCC5(C4CCC3(C2)O)O)C6=CC(=O)OC6)C)C=O)OC)OC7C(C(C(C(O7)CO)O)O)O
- Isomeric SMILES:C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2CC[C@@]3([C@H]4CC[C@@]5([C@H](CC[C@@]5([C@@H]4CC[C@@]3(C2)O)O)C6=CC(=O)OC6)C)C=O)OC)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O
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Description
Strophanthin is made up of a mixture of glycosides, mainly K-strophanthin-
β, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-D-cymaro-β-D-glycoside, and K-strophanthoside, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-Dcymaro-
β-D-gluco-α-D-glycozide. It is isolated primarily from the family
Strophantus kombe.
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Uses
Strophanthin is used in severe cardiovascular insufficiency, in particular after myocardial
infarction, for chronic cardiac insufficiency, cardiac decompensation, supraventricular
tachycardia, and ventricular arrhythmia.
