(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-prop-2-ynyl-amino]b enzoyl]amino]pentanedioic acid

Base Information

Chemical Name:(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-prop-2-ynyl-amino]b enzoyl]amino]pentanedioic acid
CAS No.:101760-45-6
Molecular Formula:C22H21 N7 O6
Molecular Weight:0
Hs Code.:
Mol file:101760-45-6.mol

Synonyms:(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-prop-2-ynyl-amino]b enzoyl]amino]pentanedioic acid;N(10)-propargylfolic acid

Suppliers and Price of (2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-prop-2-ynyl-amino]b enzoyl]amino]pentanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-prop-2-ynyl-amino]b enzoyl]amino]pentanedioic acid

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：204.49000
Density:1.52g/cm³
LogP:0.95500

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-prop-2-ynyl-amino]b enzoyl]amino]pentanedioic acid

There total 18 articles about (2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-prop-2-ynyl-amino]b enzoyl]amino]pentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 101760-46-7
diethyl N-<4-<<(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl>prop-2-ynylamino>benzoyl>-L-glutamate

: 101760-45-6
N¹⁰-propargylfolic acid

Guidance literature:: With sodium hydroxide; In ethanol; water; at 23 - 25 ℃; for 48h;

Reference yield:

: 101760-61-6
7,8-dihydro-10-propargylfolic acid

: 101760-45-6
N¹⁰-propargylfolic acid

Guidance literature:: With potassium permanganate; In methanol; Yield given;
DOI:10.1021/jm00157a600

Reference yield:

: 1118-89-4
diethyl-L-glutamate hydrochloride

: 101760-45-6
N¹⁰-propargylfolic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / dimethylsulfoxide; tetrahydrofuran / 14 h

2: aq. 0.1 N NaOH / 18 h / 25 °C

With 4-methyl-morpholine; sodium hydroxide; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/jm00157a600