7-Methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine

Base Information

Chemical Name:7-Methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine
CAS No.:133240-38-7
Molecular Formula:C24H23N7
Molecular Weight:409.494
Hs Code.:
DSSTox Substance ID:DTXSID50158025
Nikkaji Number:J555.953G
Wikidata:Q83026181
ChEMBL ID:CHEMBL296725

Synonyms:3H-Imidazo(4,5-b)pyridine, 7-methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-;7-methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine;L 158,338;L 158338;L-158,338;L-158338

Suppliers and Price of 7-Methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 7-Methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:409.20149376
Heavy Atom Count:31
Complexity:566

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1=NC2=C(C=CN=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C

Technology Process of 7-Methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine

There total 10 articles about 7-Methyl-2-propyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6635-86-5,67476-70-4
2-amino-4-methyl-3-nitropyridine

: 133240-38-7
L 158338

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / methanol / 760 Torr

2: polyphosphoric acid / 80 - 90 °C

3: 1.) NaH / 1.) DMF, 25 deg C, 20 min

4: HCOOH / 12 h / 25 °C

With formic acid; PPA; hydrogen; sodium hydride; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00113a035

Reference yield:

: 7-Methyl-2-propyl-3-[2'-(2-trityl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine

: 133240-38-7
L 158338

Guidance literature:: With formic acid; at 25 ℃; for 12h;
DOI:10.1021/jm00113a035

Reference yield:

: 106-38-7
para-bromotoluene

: 133240-38-7
L 158338

Guidance literature:: Multi-step reaction with 6 steps

2: 1.) Me₃SnN₃, 2.) aq. HCl / 1.) toluene, reflux, 24 h, 2.) 25 deg C

3: Et₃N / CH₂Cl₂ / 1.5 h / Heating

4: N-bromosuccinimide, dibenzoyl peroxide / CCl₄ / 2 h / Heating

5: 1.) NaH / 1.) DMF, 25 deg C, 20 min

6: HCOOH / 12 h / 25 °C

With hydrogenchloride; N-Bromosuccinimide; formic acid; sodium hydride; azidotrimethyltin; triethylamine; dibenzoyl peroxide; In tetrachloromethane; dichloromethane;
DOI:10.1021/jm00113a035