methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate

Base Information

Chemical Name:methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate
CAS No.:866000-51-3
Molecular Formula:C₁₄H₁₄ClN₃O₂S
Molecular Weight:323.803
Hs Code.:

Synonyms:methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate

Suppliers and Price of methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate

There total 1 articles about methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 6299-25-8
4,6-Dichloro-2-(methylthio)pyrimidine

: 6232-11-7
methyl 4-(aminomethyl)benzoate hydrochloride

: 866000-51-3
methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate

Guidance literature:: 4,6-Dichloro-2-(methylthio)pyrimidine; methyl 4-(aminomethyl)benzoate hydrochloride; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); at 70 - 80 ℃; for 24h;

With sodium hydrogencarbonate; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); water;

Reference yield: 76.0%

: 866000-51-3
methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate

: 160688-99-3
[tris(3-pyridyl)boroxin]

: 866000-52-4
4-[(2-methylsulfanyl-6-pyridin-3-yl-pyrimidin-4-ylamino)-methyl]-benzoic acid

Guidance literature:: methyl 4-[(6-chloro-2-methylsulfanyl-pyrimidin-4-ylamino)-methyl]-benzoate; [tris(3-pyridyl)boroxin]; With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; acetonitrile; at 95 ℃; for 24 - 48h;

With sodium hydroxide; water; In acetonitrile; at 95 ℃; for 1h;

With hydrogenchloride; In water; pH=5 - 7;