N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane

Base Information

• Chemical Name: N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane
• CAS No.: 217471-35-7
• Molecular Formula: C₄₂H₆₄N₂O₈
• Molecular Weight: 724.979
• Mol file: 217471-35-7.mol

Synonyms:N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane

Chemical Property of N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane

There total 2 articles about N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

3-[(N-benzyloxycarbonyl)amino]propanol (34637-22-4) + 1,20-eicosanedioyl dichloride (101702-50-5) → N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane (217471-35-7)

Guidance literature:

With dmap; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1021/jo981195k

Reference yield:

octadecane-1,18-dicarboxylic acid (2424-92-2) → N,N'-bis(N-benzyloxycarbonyl)-1,28-diamino-4,25-dioxa-5,24-dioxooctacosane (217471-35-7)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / 3 h / Heating

2: 59 percent / DMAP / CH₂Cl₂ / 24 h / 20 °C

With dmap; thionyl chloride; In dichloromethane; 1: Substitution / 2: Esterification;

DOI:10.1021/jo981195k

upstream raw materials:

3-[(N-benzyloxycarbonyl)amino]propanol

1,20-eicosanedioyl dichloride

octadecane-1,18-dicarboxylic acid