Technology Process of (2R,3S)-3,4-Bis-benzyloxy-2-methyl-butan-1-ol
There total 5 articles about (2R,3S)-3,4-Bis-benzyloxy-2-methyl-butan-1-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate;
In
methanol;
at 20 ℃;
for 0.5h;
DOI:10.1021/ja004154q
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lead(IV) acetate / benzene / 2 h / 20 °C
2: 653 mg / NaBH4 / methanol / 0.5 h / 20 °C
With
lead(IV) acetate; sodium tetrahydroborate;
In
methanol; benzene;
DOI:10.1021/ja004154q
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium tert-butoxide; n-BuLi / tetrahydrofuran; hexane / 0.17 h / -45 °C
1.2: (-)-methoxydiisopinocampheylborane / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.3: 56 percent / boron trifluoride etherate / tetrahydrofuran; hexane / 3 h / -78 °C
2.1: tetrabutylammonium iodide; NaH / dimethylformamide; various solvent(s) / 0.5 h / 0 °C
2.2: 1.34 g / dimethylformamide; various solvent(s) / 0 - 20 °C
3.1: 73 percent / OsO4; 4-methylmorpholine N-oxide / acetone; H2O; toluene / 20 °C
4.1: lead(IV) acetate / benzene / 2 h / 20 °C
5.1: 653 mg / NaBH4 / methanol / 0.5 h / 20 °C
With
lead(IV) acetate; sodium tetrahydroborate; osmium(VIII) oxide; n-butyllithium; potassium tert-butylate; tetra-(n-butyl)ammonium iodide; sodium hydride; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; methanol; hexane; water; N,N-dimethyl-formamide; acetone; toluene; benzene;
1.1: Brown crotylboration / 1.2: Brown crotylboration / 1.3: Brown crotylboration;
DOI:10.1021/ja004154q
