3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide

Base Information

• Chemical Name: 3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide
• CAS No.: 1227783-82-5
• Molecular Formula: C₁₉H₂₁FN₂O₃
• Molecular Weight: 344.386
• Mol file: 1227783-82-5.mol

Synonyms:3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide

Chemical Property of 3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide

There total 2 articles about 3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

→ 3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide (1227783-82-5)

Guidance literature:

Reference yield:

3-(4-fluorophenyl)propanoic acid (459-31-4) + [(4-nitrophenyl)methyl](propyl)amine (62869-74-3) → 3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide (1227783-82-5)

Guidance literature:

With dicyclohexyl-carbodiimide; for 0.333333h;

DOI:10.1016/j.bmc.2010.04.078

Reference yield: 94.0%

3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropionamide (1227783-82-5) → N-propyl-N-(4-amino-benzyl)-3-(4-flourophenyl)propionamide (1227783-81-4)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; under 760.051 Torr;

upstream raw materials:

3-(4-fluorophenyl)propanoic acid

[(4-nitrophenyl)methyl](propyl)amine

Downstream raw materials:

N-propyl-N-(4-amino-benzyl)-3-(4-flourophenyl)propionamide

3-(4-fluorophenyl)-N-(4-nitrobenzyl)-N-propylpropan-1-amine