syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene

Base Information

• Chemical Name: syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene
• CAS No.: 34098-60-7
• Molecular Formula: C₁₃H₁₄O
• Molecular Weight: 186.254
• Mol file: 34098-60-7.mol

Synonyms:syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene

Chemical Property of syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene

There total 2 articles about syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

bromobenzene (108-86-1,52753-63-6) + bicyclo<2.2.1>hept-2-en-7-one (694-71-3) → syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene (34098-60-7)

Guidance literature:

bromobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

bicyclo<2.2.1>hept-2-en-7-one; In tetrahydrofuran; at 22 ℃; for 12h; Further stages.;

DOI:10.1021/ja010684q

Reference yield:

phenyllithium (591-51-5) + bicyclo<2.2.1>hept-2-en-7-one (694-71-3) → syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene (34098-60-7)

Guidance literature:

DOI:10.1139/v71-362

Reference yield: 88.0%

chloromethyl methyl ether (107-30-2) + syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene (34098-60-7) → syn-7-methoxymethoxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene (361548-09-6)

Guidance literature:

syn-7-hydroxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene; With potassium hydride; In tetrahydrofuran; for 1h;

chloromethyl methyl ether; In tetrahydrofuran; for 24h; Further stages.;

DOI:10.1021/ja010684q

upstream raw materials:

phenyllithium

bicyclo<2.2.1>hept-2-en-7-one

bromobenzene

Downstream raw materials:

syn-7-methoxymethoxy-anti-7-phenyl-bicyclo[2.2.1]hept-2-ene

Refernces