3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine

Base Information

Chemical Name:3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine
CAS No.:353292-73-6
Molecular Formula:C₂₀H₁₄ClF₄N₃O₆
Molecular Weight:503.794
Hs Code.:

Synonyms:3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine

Suppliers and Price of 3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine

There total 4 articles about 3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.9%

: 590-28-3
potassium cyanate

: 2-({3-[2-chloro-4-fluoro-5-(4,4,4-trifluoro-3-oxobutanamido)phenoxy]pyridin-2-yl}oxy)acetic acid ethyl ester

: 353292-73-6
3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine

Guidance literature:: With acetic acid; In 5,5-dimethyl-1,3-cyclohexadiene; at 40 - 85 ℃; for 10.5h; Temperature; Reagent/catalyst;

Reference yield:

: 353292-54-3
ethyl 2-{[3-(5-amino-2-chloro-4-fluorophenoxy)pyridin-2-yl]oxy}acetate

: 353292-73-6
3-{2-chloro-4-fluoro-5-[2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(ethoxycarbonyl)methoxypyridine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / n-heptane / 16.5 h / 90 °C / 630.06 - 652.57 Torr / Dean-Stark

2: acetic acid / 5,5-dimethyl-1,3-cyclohexadiene / 10.5 h / 40 - 85 °C

With sodium hydrogencarbonate; acetic acid; In 5,5-dimethyl-1,3-cyclohexadiene; n-heptane;