4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide

Base Information

• Chemical Name: 4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide
• CAS No.: 1041464-61-2
• Molecular Formula: C₁₁H₁₄N₄O₃S
• Molecular Weight: 282.323
• Mol file: 1041464-61-2.mol

Synonyms:4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide

Chemical Property of 4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide

There total 1 articles about 4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

4-azidobenzenesulfonamide (36326-86-0) + 2-methyl-but-3-yn-2-ol (115-19-5) → 4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide (1041464-61-2)

Guidance literature:

With copper(II) sulfate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; for 3.5h;

DOI:10.1021/ol8011088

Reference yield: 15.0%

4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide (1041464-61-2) → 4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonyl azide (1041464-62-3)

Guidance literature:

With triflic azide; sodium hydrogencarbonate; copper(II) sulfate; In water; toluene; tert-butyl alcohol; at 20 ℃; for 40h;

DOI:10.1021/ol8011088

upstream raw materials:

4-azidobenzenesulfonamide

2-methyl-but-3-yn-2-ol

Downstream raw materials:

4-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)benzenesulfonyl azide