(Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester

Base Information

• Chemical Name: (Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester
• CAS No.: 71260-68-9
• Molecular Formula: C₄₇H₇₉Br₃NO₇P
• Molecular Weight: 1040.83
• Mol file: 71260-68-9.mol

Synonyms:(Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester

Chemical Property of (Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester

There total 2 articles about (Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aniline (62-53-3) → (Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester (71260-68-9)

Guidance literature:

Multi-step reaction with 2 steps

2: 1-methyl-imidazole

With 1-methyl-1H-imidazole;

Reference yield:

1,2-dioleoylglycerol (2442-61-7,3738-74-7,22202-42-2,24529-88-2,26540-69-2,33735-55-6,38738-56-6,98719-67-6) + 2,2,2-tribromoethyl phosphoranilidochloridate (71260-65-6) → (Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester (71260-68-9)

Guidance literature:

With 1-methyl-1H-imidazole;

Reference yield:

(Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-[phenylamino-(2,2,2-tribromo-ethoxy)-phosphoryloxy]-ethyl ester (71260-68-9) → dioleoylphosphatidylethanolamine (2462-63-7,4004-05-1,5683-50-1,5683-54-5,7768-07-2,16777-83-6,16810-06-3,19805-18-6)

Guidance literature:

Multi-step reaction with 4 steps

1: isopentyl nitrite, Py

2: 2,4,6-triisopropylbenzenesulfonyl chloride, Py

3: Zn, Py, AcOH

4: SiO₂

With pyridine; 2,4,6-triisopropylphenylsulfonyl chloride; silica gel; acetic acid; zinc; isopentyl nitrite;

upstream raw materials:

1,2-dioleoylglycerol

2,2,2-tribromoethyl phosphoranilidochloridate

aniline

Downstream raw materials:

dioleoylphosphatidylethanolamine

(Z)-Octadec-9-enoic acid 1-((Z)-octadec-9-enoyloxymethyl)-2-{(2,2,2-tribromo-ethoxy)-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-ethyl ester

(Z)-Octadec-9-enoic acid 2-{hydroxy-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-1-((Z)-octadec-9-enoyloxymethyl)-ethyl ester