phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate

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Chemical Name:phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate
CAS No.:918650-51-8
Molecular Formula:C₅₈H₆₈N₄O₁₂Si
Molecular Weight:1041.28
Hs Code.:

phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate

Synonyms:phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate

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Chemical Property of phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate

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Technology Process of phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate

There total 1 articles about phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 918650-50-7
(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoic acid

: 918650-15-4
phenylmethyl (2S)-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)-2-[(triphenylmethyl)amino]propanoate

: 918650-51-8
phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate

Guidance literature:: phenylmethyl (2S)-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)-2-[(triphenylmethyl)amino]propanoate; With triethylsilane; water; trifluoroacetic acid; In dichloromethane; for 4h;

(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoic acid; With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃; for 14h;

Reference yield:

: 918650-51-8
phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate

: 918650-57-4
C₅₃H₅₆N₄O₁₂

Guidance literature:: phenylmethyl (2S)-2-{(2S)-2-[(tert-butoxy)-N-methylcarbonylamino]-4-(7-methoxy-2-phenyl(4-quinolyl)oxy)butanoylamino}-3-(3-{(2S)-2-[(3,3-dimethyl-3-silabutyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]ethyl}phenoxy)propanoate; With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 3h;

With hydrogenchloride; water; In tetrahydrofuran; ethyl acetate;