N-(4-chlorophenyl)-2-hydroxy-2-phenylacetamide

Base Information

Chemical Name:N-(4-chlorophenyl)-2-hydroxy-2-phenylacetamide
CAS No.:10295-53-1
Molecular Formula:C₁₄H₁₂ClNO₂
Molecular Weight:261.708
Hs Code.:
DSSTox Substance ID:DTXSID601259555
Nikkaji Number:J3.538.798F

Synonyms:4'-chloromandelanilide;Cambridge id 5278376;N-(4-chlorophenyl)-2-hydroxy-2-phenylacetamide;Oprea1_325880;DTXSID601259555;HMS1580K05;J3.538.798F;N-(4-Chlorophenyl)benzene(2-hydroxyacetamide);N-(4-Chlorophenyl)-alpha-hydroxybenzeneacetamide;SR-01000203040;SR-01000203040-1;10295-53-1

Suppliers and Price of N-(4-chlorophenyl)-2-hydroxy-2-phenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(4-chlorophenyl)-2-hydroxy-2-phenylacetamide

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:261.0556563
Heavy Atom Count:18
Complexity:271

Purity/Quality:

Safty Information:

Pictogram(s):
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MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(=O)NC2=CC=C(C=C2)Cl)O

Technology Process of N-(4-chlorophenyl)-2-hydroxy-2-phenylacetamide

There total 12 articles about N-(4-chlorophenyl)-2-hydroxy-2-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 611-71-2,611-72-3,17199-29-0,90-64-2
MANDELIC ACID

: 13165-68-9,52867-11-5
N-(4-chloro-phenyl)-sulfur imide oxide

: 10295-53-1
α-hydroxy-N-(4-chlorophenyl)phenylacetamide

Guidance literature:: at 25 ℃; for 3h;
DOI:10.1016/S0040-4039(00)84412-3

Reference yield: 96.0%

: 28193-68-2
N-(4-chlorophenyl)-α-oxophenylacetamide

: 10295-53-1
α-hydroxy-N-(4-chlorophenyl)phenylacetamide

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sodium acetate; nickel diacetate; In tetrahydrofuran; at 20 - 60 ℃; for 8h; chemoselective reaction; Inert atmosphere;
DOI:10.1039/c4cc02744b