2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone

Base Information

• Chemical Name: 2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone
• CAS No.: 297154-61-1
• Molecular Formula: C₅₉H₄₀O
• Molecular Weight: 764.966
• Mol file: 297154-61-1.mol

Synonyms:2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone

Chemical Property of 2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone

There total 7 articles about 2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dibromotoluene (1611-92-3) → 2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone (297154-61-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 91 percent / aq. K₂CO₃; Pd(PPh₃)4 / ethanol; toluene / 96 h / Heating

2: 94 percent / NBS / CCl₄ / 18 h / Heating

3: 31 percent / aq. NaOH; benzyltriethylammonium chloride / CH₂Cl₂ / 18 h / Heating

4: 59 percent / nBu₄NOH / dioxane; methanol / 0.25 h / Heating

With sodium hydroxide; N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetra(n-butyl)ammonium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In 1,4-dioxane; methanol; tetrachloromethane; ethanol; dichloromethane; toluene; 1: Suzuki coupling / 2: bromination / 4: Knoevenagel condensation;

DOI:10.1021/ja000832x

Reference yield:

3-bromobiphenyl (2113-57-7) → 2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone (297154-61-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent / Pd(PPh₃)4; CuI; piperidine / 5 h / 80 °C

2: 81 percent / iodine; DMSO / 18 h / Heating

3: 59 percent / nBu₄NOH / dioxane; methanol / 0.25 h / Heating

With piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetra(n-butyl)ammonium hydroxide; iodine; dimethyl sulfoxide; In 1,4-dioxane; methanol; 1: Hagihara coupling / 2: oxidation / 3: Knoevenagel condensation;

DOI:10.1021/ja000832x

Reference yield:

5'-methyl-1,1':3',1''-terphenyl (33733-07-2) → 2,5-bis(3,5-diphenylphenyl)-3-phenyl-4-(3-biphenyl)cyclopentadienone (297154-61-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent / NBS / CCl₄ / 18 h / Heating

2: 31 percent / aq. NaOH; benzyltriethylammonium chloride / CH₂Cl₂ / 18 h / Heating

3: 59 percent / nBu₄NOH / dioxane; methanol / 0.25 h / Heating

With sodium hydroxide; N-Bromosuccinimide; tetra(n-butyl)ammonium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In 1,4-dioxane; methanol; tetrachloromethane; dichloromethane; 1: bromination / 3: Knoevenagel condensation;

DOI:10.1021/ja000832x

upstream raw materials:

3,5-dibromotoluene

3-bromobiphenyl

5'-methyl-1,1':3',1''-terphenyl

phenylacetylene

Refernces