Technology Process of 2-(4-oxo-6-phenyl-1,4-dihydro-pyridazin-3-yl)-benzoic acid
There total 1 articles about 2-(4-oxo-6-phenyl-1,4-dihydro-pyridazin-3-yl)-benzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: acetic anhydride / toluene / 1.5 h / Heating
2: ammonium acetate / 9 h / 190 - 200 °C
3: 94 percent / phosphorus pentachloride, phosphorus oxychloride / 3.5 h / Heating
4: 74 percent / H2 / 10percent Pd/C, magnesium oxide / 2-methoxy-ethanol / 760 Torr / Ambient temperature
5: 76 percent / potassium acetate, iodine / ethanol / 2 h / Heating
With
ammonium acetate; phosphorus pentachloride; hydrogen; iodine; potassium acetate; acetic anhydride; trichlorophosphate;
palladium on activated charcoal; magnesium oxide;
In
ethanol; 2-methoxy-ethanol; toluene;
DOI:10.1021/jm00147a034
- Guidance literature:
-
Multi-step reaction with 4 steps
1: acetic anhydride / toluene / 1.5 h / Heating
2: ammonium acetate / 9 h / 190 - 200 °C
3: 94 percent / phosphorus pentachloride, phosphorus oxychloride / 3.5 h / Heating
4: 74 percent / H2 / 10percent Pd/C, magnesium oxide / 2-methoxy-ethanol / 760 Torr / Ambient temperature
With
ammonium acetate; phosphorus pentachloride; hydrogen; acetic anhydride; trichlorophosphate;
palladium on activated charcoal; magnesium oxide;
In
2-methoxy-ethanol; toluene;
DOI:10.1021/jm00147a034
