10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one

Base Information

• Chemical Name: 10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one
• CAS No.: 1301159-90-9
• Molecular Formula: C₂₈H₂₀O₆
• Molecular Weight: 452.463
• Mol file: 1301159-90-9.mol

Synonyms:10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one

Chemical Property of 10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one

There total 5 articles about 10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

10-hydroxy-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one (1301159-85-2) + chloromethyl methyl ether (107-30-2) → 10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one (1301159-90-9)

Guidance literature:

10-hydroxy-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one; With sodium hydride; In acetone; at 0 ℃; for 0.5h;

chloromethyl methyl ether; In acetone; at 0 - 20 ℃; for 3.16667h;

DOI:10.1016/j.ejmech.2011.01.051

Reference yield:

2,3-dimethoxybenzoic acid (1521-38-6) → 10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one (1301159-90-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: oxalyl dichloride / dichloromethane / 24 h / 20 °C

2.1: aluminum (III) chloride / diethyl ether / 12 h / 0 - 20 °C / Inert atmosphere

2.3: 36 h / 110 °C

3.1: water; hydrogen bromide; acetic acid / 12 h / 120 °C / Inert atmosphere

4.1: diphenylether / 4 h / 175 °C

5.1: sodium hydride / acetone / 0.5 h / 0 °C

5.2: 3.17 h / 0 - 20 °C

With aluminum (III) chloride; oxalyl dichloride; water; hydrogen bromide; sodium hydride; acetic acid; In diphenylether; diethyl ether; dichloromethane; acetone; 2.1: Friedel Crafts acylation;

DOI:10.1016/j.ejmech.2011.01.051

Reference yield:

2,3-dimethoxybenzoyl chloride (7169-06-4) → 10-(methoxymethoxy)-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one (1301159-90-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: aluminum (III) chloride / diethyl ether / 12 h / 0 - 20 °C / Inert atmosphere

1.3: 36 h / 110 °C

2.1: water; hydrogen bromide; acetic acid / 12 h / 120 °C / Inert atmosphere

3.1: diphenylether / 4 h / 175 °C

4.1: sodium hydride / acetone / 0.5 h / 0 °C

4.2: 3.17 h / 0 - 20 °C

With aluminum (III) chloride; water; hydrogen bromide; sodium hydride; acetic acid; In diphenylether; diethyl ether; acetone; 1.1: Friedel Crafts acylation;

DOI:10.1016/j.ejmech.2011.01.051

upstream raw materials:

3,4,5-trimethoxy-9H-xanthen-9-one

3,4,5-trihydroxy-9H-xanthen-9-one

10-hydroxy-2,2-diphenyl-6H-[1,3]dioxolo[4,5-c]xanthen-6-one

chloromethyl methyl ether