21-hydroxypregn-4-ene-3,20-dione 21-(3-phenylpropionate)

Base Information

• Chemical Name: 21-hydroxypregn-4-ene-3,20-dione 21-(3-phenylpropionate)
• CAS No.: 14007-50-2
• Molecular Formula: C30H38 O4
• Molecular Weight: 462.629
• Mol file: 14007-50-2.mol

Synonyms:Corticosterone,11-deoxy-, 21-hydrocinnamate (6CI); Corticosterone, deoxy-, hydrocinnamate(8CI); Hydrocinnamic acid, ester with deoxycorticosterone (8CI);Deoxycorticosterone hydrocinnamate; Deoxycorticosterone phenylpropionate;Desoxycorticosterone phenylpropionate

Chemical Property of 21-hydroxypregn-4-ene-3,20-dione 21-(3-phenylpropionate)

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 601.8°Cat760mmHg
• Flash Point: 254.8°C
• PSA: 60.44000
• Density: 1.15g/cm³
• LogP: 5.87960

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 21-hydroxypregn-4-ene-3,20-dione 21-(3-phenylpropionate)

There total 3 articles about 21-hydroxypregn-4-ene-3,20-dione 21-(3-phenylpropionate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3β-hydroxy-21-(3-phenyl-propionyloxy)-pregn-5-en-20-one (115292-00-7) → 21-(3-phenyl-propionyloxy)-pregn-4-ene-3,20-dione (14007-50-2)

Guidance literature:

With cyclohexanone; aluminum isopropoxide; toluene;

Reference yield:

21-diazo-3β-hydroxy-pregn-5-en-20-one (33769-71-0) → 21-(3-phenyl-propionyloxy)-pregn-4-ene-3,20-dione (14007-50-2)

Guidance literature:

Multi-step reaction with 2 steps

2: aluminium isopropylate; cyclohexanone; toluene

With cyclohexanone; aluminum isopropoxide; toluene;

Reference yield:

3-Phenylpropionic acid (501-52-0) → 21-(3-phenyl-propionyloxy)-pregn-4-ene-3,20-dione (14007-50-2)

Guidance literature:

Multi-step reaction with 2 steps

2: aluminium isopropylate; cyclohexanone; toluene

With cyclohexanone; aluminum isopropoxide; toluene;

upstream raw materials:

3β-hydroxy-21-(3-phenyl-propionyloxy)-pregn-5-en-20-one

21-diazo-3β-hydroxy-pregn-5-en-20-one

3-Phenylpropionic acid

Downstream raw materials:

3-benzyloxy-21-(3-phenyl-propionyloxy)-pregna-3,5-dien-20-one