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(R)-3-(4-nitrophenyl)-2-methylpropanoic acid

Base Information
  • Chemical Name:(R)-3-(4-nitrophenyl)-2-methylpropanoic acid
  • CAS No.:851968-99-5
  • Molecular Formula:C10H11NO4
  • Molecular Weight:209.202
  • Hs Code.:
(R)-3-(4-nitrophenyl)-2-methylpropanoic acid

Synonyms:(R)-3-(4-nitrophenyl)-2-methylpropanoic acid

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Chemical Property of (R)-3-(4-nitrophenyl)-2-methylpropanoic acid
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Technology Process of (R)-3-(4-nitrophenyl)-2-methylpropanoic acid

There total 6 articles about (R)-3-(4-nitrophenyl)-2-methylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With (R)-1,1'-di[(3,4,5-Me3C6H2)2P]-9,9'-spirobifluorene*Ru(OAc)2; hydrogen; In methanol; at 25 - 28 ℃; for 30h; under 4560 Torr; Title compound not separated from byproducts;
DOI:10.1002/anie.200462072
Guidance literature:
2-methyl-3-(4-nitrophenyl)propanal; With sodium dihydrogenphosphate; In tetrahydrofuran; tert-butyl alcohol; at 20 ℃;
With sodium chlorite; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 3h;
DOI:10.1021/ja106593m
Guidance literature:
2-methyl-3-(4-nitrophenyl)propanoic acid (1R,2S)-1,2-bis(2-methoxyphenyl)-2-(2-methylpropoxy)ethyl ester; With lithium hydroxide; water; In tetrahydrofuran; methanol; for 48h; Reflux;
With water; sodium hydrogencarbonate;
With hydrogenchloride; In water; optical yield given as %ee;
DOI:10.1016/j.tetasy.2009.02.004
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