Cortivazol

Base Information

• Chemical Name: Cortivazol
• CAS No.: 1110-40-3
• Molecular Formula: C32H38 N2 O5
• Molecular Weight: 530.664
• European Community (EC) Number: 214-175-8
• UNII: YM183K0H63
• DSSTox Substance ID: DTXSID40149442
• Nikkaji Number: J34.127D
• Wikipedia: Cortivazol
• Wikidata: Q2421270
• NCI Thesaurus Code: C80812
• Pharos Ligand ID: G69SB43KX3NR
• Metabolomics Workbench ID: 153883
• ChEMBL ID: CHEMBL2105842
• Mol file: 1110-40-3.mol

Synonyms:cortivazol;Dilaster;H-3625;Idaltim

Chemical Property of Cortivazol

Chemical Property:

• Vapor Pressure: 9.21E-20mmHg at 25°C
• Melting Point: 160-165° and 229-230°
• Boiling Point: 686°Cat760mmHg
• PKA: 12.43±0.70(Predicted)
• Flash Point: 368.7°C
• PSA: 101.65000
• Density: 1.33g/cm³
• LogP: 4.30060
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 530.27807232
• Heavy Atom Count: 39
• Complexity: 1100

Purity/Quality:

99% ^*data from raw suppliers

CORTIVAZOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2C3C=C(C4=CC5=C(CC4(C3C(CC2(C1(C(=O)COC(=O)C)O)C)O)C)C=NN5C6=CC=CC=C6)C
• Isomeric SMILES: C[C@@H]1C[C@H]2[C@@H]3C=C(C4=CC5=C(C[C@@]4([C@H]3[C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)O)C)O)C)C=NN5C6=CC=CC=C6)C
• Recent ClinicalTrials: A Phase III Study to Evaluate Efficacy of Botulinum Toxin for Treating Epicondylitis
• Recent EU Clinical Trials: Evaluation de trois types d’infiltrations dans le cadre du traitement des épicondylalgies latérales : Leukocyte – Platelet Rich Plasma (L-PRP) versus Toxine botulique de type A (Xeomin?, MERZ) versus Glucocortico?des – Essai thérapeutique multicentrique contr?lé randomisé en double aveugle à trois bras parallèles
• Uses: Glucocorticoid.
• Therapeutic Function: Glucocorticoid

Technology Process of Cortivazol

There total 3 articles about Cortivazol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ cortivazol (1110-40-3)

Guidance literature:

Reference yield:

→ 21-acetoxy-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-2'H-pregna-4,6-dieno[3,2-c]pyrazol-20-one (1110-40-3)

Guidance literature:

Reference yield:

→ 21-acetoxy-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-2'H-pregna-4,6-dieno[3,2-c]pyrazol-20-one (1110-40-3)

Guidance literature:

6.16α-Dimethyl-17α.20.20.21-bismethylendioxy-4.6-pregnadien-11β-ol-<3.2-c>-2'-phenyl-pyrazol , 60percent HCO2H --> Freie Oxy-Oxo-Seitenkette , Acetylierung ---> X;

DOI:10.1021/ja00885a032

Downstream raw materials:

cortivazol

Refernces